侯 勇
西南大学 教授，博士生导师
学习工作经历
1998-2002, 河北农业大学本科生；
2002-2007，西南农业大学博士生（硕博连读）；
2007-2017，西南大学副教授；
2017至今， 西南大学教授，博士生导师
2022至今， 西部（重庆）科学城种质创制大科学中心，家蚕种质创制团队科研人员
研究领域
以昆虫生长及变态发育机制为研究方向，以家蚕贮藏蛋白SPs、cathepsin-L、p37k蛋白酶、羧肽酶、CPAP3型表皮蛋白等为靶标，利用组学手段对变态发育时期的家蚕表皮、血液、蜕皮液、消化液等样品进行分析，同时开展基因功能研究，先后在Insect Biochemistry and Molecular Biology、Proteomics、Insect Science、Protein Science、Journal of General Virology、International Journal of Molecular Sciences、Biochemical and Biophysical Research Communications、Bioscience Biotechnology and Biochemistry、 Proteome Science、DNA Sequence、中国农业科学、生物工程学报、蚕业科学等杂志发表论文30余篇，主持国家自然科学基金面上项目、国家自然科学基金青年项目、重庆市自然科学基金、教育部中央高校重点项目、烟草重大专项（子课题）等项目10余项，培养博士研究生3人，硕士研究生19人。担任Insect Biochemistry and Molecular Biology、Insect science、Gene、蚕业科学等多篇杂志审稿人, 任教育部学位论文评审专家。
成果情况
代表性论文/论著：
1.Hou Y, Yang L, Xu S, Zhang Y, Cheng Y, Li Y, Gong J, Xia Q*. Trypsin-type serine protease p37k hydrolyzes CPAP3-type cuticle proteins in the molting fluid of the silkworm Bombyx mori. Insect Biochem Mol Biol. 2021, 137:103610.
2.Yang H, Zhang R, Zhang Y, Liu Q, Li Y, Gong J, Hou Y*. Cathepsin-L is involved in degradation of fat body and programmed cell death in Bombyx mori. Gene. 2020, 760:144998.
3. Zhang Z, Yan J, Liu Q, Zhang Y, Gong J, Hou Y*. Genome-Wide Analysis and Hormone Regulation of Chitin Deacetylases in Silkworm. Int J Mol Sci. 2019, 4; 20(7).
4. Yang H, Li J, Liu Q, Zhang Z, Gong J, Hou Y*. Purification and characterization of two cysteine proteinase inhibitors from silkworm, Bombyx mori. Biochem Biophys Res Commun. 2018. pii: S0006-291X(18)31784-4. doi:
5. Tian S, Zhang Z, Zhang R, Liu Q, Xu S, Gong J, Hou Y*. Analysis of cysteine protease inhibitor gene (BmCPI) promoter activity in silkworms using bac-to-bac baculovirus systems. Biosci Biotechnol Biochem. 2018, 82(9):1488-1496. doi:doi: 10.1080/09168451.
6. Li ZL, Tian S, Yang H, Zhou X, Xu SP, Zhang ZY, Gong J, Hou Y*, Xia QY. Genome-wide identification of chitin-binding proteins and characterization of BmCBP1 in the silkworm, Bombyx mori. Insect Sci. 2017 . doi: 10.1111/1744-7917.
7. Hou Y, Zhang Y, Gong J, Tian S, Li J, Dong Z, Guo C, Peng L, Zhao P, Xia Q. Comparative proteomics analysis of silkworm hemolymph during the stages of metamorphosis via liquid chromatography and mass spectrometry. Proteomics. 2016, 16(9):1421-31.
8. Gong J, Tian S, Zhou X, Yang H, Zhu Y*, Hou Y*. Transcriptional Response of Silkworm (Bombyx mori) Eggs to O? or HCl Treatment. Int J Mol Sci. 2016, 17(12), pii: E1838.
9. Hou Y, Li J, Li Y, Dong Z, Xia Q, Yuan YA. Crystal structure of Bombyx mori arylphorins reveals a 3:3 heterohexamer with multiple papain cleavage sites. Protein Sci. 2014, 23(6):735-46.
10. Hou Y, Xia Q, Yuan YA. Crystal structure of Bombyx mori nucleopolyhedrovirus ORF75 reveals a pseudo-dimer of thiol oxidase domains with a putative substrate-binding pocket. J Gen Virol. 2012,93:2142-51
11. Yong Hou, Yong Zou, Fei Wang, Jing Gong, Xiaowu Zhong, Qingyou Xia, Ping Zhao. Comparative analysis of proteome maps of silkworm hemolymph during different developmental stages. Proteome Science, 2010, 8:45
12. Hou Y, Xia Q , Zhao P, Zou Y, Liu H, Guan J, Gong J, Xiang Z. Studies on middle silk gland and posteriorsilk gland of silkworm (Bombyx mori) using two-dimensional electrophoresis and mass spectrometry. Insect Biochemistry and Molecular Biology 2007,37:486-496.
13. Xia Q, Zhou Z, Lu C, Cheng D, Dai F, Li B, Zhao P, Zha X, Cheng T, Chai C, Pan G, Xu J, Liu C, Lin Y, Qian J, Hou Y, Wu Z, Li G, Pan M, Li C, Shen Y, Lan X, Yuan L, Li T, Xu H, Yang G, Wan Y, Zhu Y, Yu M, Shen W, Wu D, Xiang Z, Yu J, Wang J, Li R, Shi J, Li H, Li G, Su J, Wang X, Li G, Zhang Z, Wu Q, Li J, Zhang Q, Wei N, Xu J, Sun H, Dong L, Liu D, Zhao S, Zhao X, Meng Q, Lan F, Huang X, Li Y, Fang L, Li C, Li D, Sun Y, Zhang Z, Yang Z, Huang Y, Xi Y, Qi Q, He D, Huang H, Zhang X, Wang Z, Li W, Cao Y, Yu Y, Yu H, Li J, Ye J, Chen H, Zhou Y, Liu B, Wang J, Ye J, Ji H, Li S, Ni P, Zhang J, Zhang Y, Zheng H, Mao B, Wang W, Ye C, Li S, Wang J, Wong GK, Yang H; Biology Analysis Group. A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science, 2004, 306:1937-1940.
14. 李懿，周小英，黎治浪，李建伟，陈世达，郭超，侯勇*,赵萍.家蚕组织蛋白酶基因家族的鉴定及表达特征分析, 生物工程学报,2016, 32(1), 1-13.
15. 李建伟，李懿，周小英，黎治浪，陈世达，田莎，侯勇*，夏庆友。家蚕半胱氨酸蛋白酶抑制剂BmCPI40鉴定及时空表达特征,中国农业科学，2015,48(13):2645-2655
16. 李建伟，王阿蓉，李懿，黎治浪，龚竞，侯勇*，夏庆友。家蚕芳基贮藏蛋白新成员BmSP3的基因克隆与表达分析，蚕业科学，2014,40(4),613-619。
联系方式
Email：yhou@swu.edu.cn