张勇
博士，西南大学生命科学学院/电子科技大学生命科学与技术学院，教授，博士生导师，“长江学者奖励计划”特聘教授。
个人简介
专注于植物基因组编辑及合成生物学相关教学、科研工作开展了系列研究工作：
1. 在Nature Plants、Molecular Plant、Nature Communications等期刊发表论文150余篇，Google Scholar引用1.25万余次，H指数45，得到Science、Nature、Nature Reviews Genetics等高影响力期刊引用及评述，19篇论文入选ESI高被引论文，7篇论文入选ESI热点论文；
2. 申请发明专利43项，授权26项，搭建了植物基因组编辑功能元件挖掘、工具库构建及种质创新应用的知识产权链条；
3. 入选科睿唯安2022-2024年植物与动物科学“全球高被引科学家”，评为四川省学术和技术带头人、四川省有突出贡献的优秀专家；
4. 主持国家自然科学基金、国家转基因重大专项课题、四川省杰出青年科技人才基金等科研项目；
5. 受邀在第七届国际作物科学大会（2017）、中国作物学会全国代表大会（2019，2024）、中国农业生物技术学会全国代表大会（2021、2023、2025）、中国植物生理与植物分子生物学全国学术年会暨成立六十周年庆祝大会（2023）等会议做专题报告；
6. 当选中国遗传学会理事、中国生物工程学会理事、中国遗传学会基因组编辑分会第一、二届委员、四川省遗传学会第八、九、十届理事会理事及多个省部级重点实验室学术委员会委员。
教育背景
1996年09月—2000年06月，西南（农业）大学，园艺园林学院，园艺学专业，本科
2000年09月—2003年06月，西南（农业）大学，园艺园林学院，果树学专业，硕士
2003年09月—2006年06月，南开大学，生命科学学院，遗传学专业，博士
工作经历
2023年10月-今 西南大学 生命科学学院 教授
2023年10月-今 西部（重庆）科学城种质创制大科学中心 杨树种质创制团队科研人员
2015年08月-今 电子科技大学 生命科学与技术学院， 教授
2013年07月-2013年11月 明尼苏达大学 医学院/基因组工程中心， 访问教授
2011年08月-2012年10月 明尼苏达大学 医学院/基因组工程中心， 高级研究员
2010年07月-2011年07月 明尼苏达大学 医学院/基因组工程中心 博士后
2008年07月-2015年07月 电子科技大学 生命科学与技术学院 副教授
2007年01月-2010年03月 四川农业大学 农学院 博士后
2006年06月-2008年06月 电子科技大学 生命科学与技术学院 讲师
学术兼职
2023年11月-2028年11月 中国遗传学会第十一届理事会， 理事
2021年05月-2026年05月 中国生物工程学会第七届理事会 理事
2019年12月-2023年12月 中国遗传学会基因编辑与合成分会 委员
2017年05月-2023年05月 中国生物工程学会林业生物工程委员会 委员
2019年08月-2024年08月 四川省遗传学会第十届理会理事
2025年04月-2027年04月 Journal of Integrative Plant Biology Editor
2025年04月-今 Genome Biology，Guest Editor
2019年05月-今 Frontiers in Genome Editing，Guest Associate Editor
代表论文（下划线为ESI高被引论文）
1. He Y, Liao S, Ren Q, Tang X, Zheng X, Qi Y* and Zhang Y*. 2025. CRISPR-Cas12i confers efficient genome editing and gene regulation in plants. Plant Physiol, 198. (corresponding author)
2. He Y, Liu S, Zheng X, Qi Y* and Zhang Y*. 2025. Systemic evaluation of the inhibitory effects of 4 anti-CRISPR systems on different Cas12a nucleases in rice. Plant Physiol, 197. (corresponding author)
3. Liu S, He Y, Fan T, Zhu M, Qi C, Ma Y, Yang M, Yang L, Tang X, Zhou J, Zhong Z, An X*, Qi Y* and Zhang Y*. 2025. PAM-relaxed and temperature-tolerant CRISPR-Mb3Cas12a single transcript unit systems for efficient singular and multiplexed genome editing in rice, maize, and tomato. Plant Biotechnol J, 23: 156-173. (corresponding author)
4. Zheng X, Ding L, Liu G, Guo J, Zhang Z, Zhang J, Pang Y, Tang X, Ren Q, Liu B, Huang L, Zhang T* and Zhang Y*. 2025a. Development and activity evaluation of a highly efficient CRISPR-Cas genome editing system in larch. Horticultural Plant Journal. (corresponding author)
5. Zheng X, Tang X, Wu Y, Zheng X, Zhou J, Han Q, Tang Y, Fu X, Deng J, Wang Y, Wang D, Zhang S, Zhang T*, Qi Y* and Zhang Y*. 2025. An efficient CRISPR-Cas12a-mediated MicroRNA knockout strategy in plants. Plant Biotechnol J, 23: 128-140. (corresponding author)
6. Zhou J, Pang R, Han Y, Guo Y, Wang Y, Yang H, Wang W, Fu X, Zhang R, Zheng X, Zhang T, Zhang Y* and Wang Q*. 2025. CRISPR-Cas9-mediated knockout of OsKCS11 in rice reveals potential crosstalk between very-long-chain fatty acids and cytokinin. Plant J, 122: e70208. (corresponding author)
7. Fan T, Cheng Y, Wu Y, Liu S, Tang X, He Y, Liao S, Zheng X, Zhang T*, Qi Y* and Zhang Y*. 2024. High performance TadA-8e derived cytosine and dual base editors with undetectable off-target effects in plants. Nat Commun, 15: 5103. (corresponding author)
8. Chen X, Zhong Z, Tang X, Yang S, Zhang Y, Wang S, Liu Y, Zhang Y, Zheng X, Zhang Y* and Feng X*. 2024. Advancing PAM-less genome editing in soybean using CRISPR-SpRY. Hortic Res. (corresponding author)
9. Han Y, Liu G, Wu Y, Bao Y, Zhang Y* and Zhang T*. 2024. CrisprStitch: Fast evaluation of the efficiency of CRISPR editing systems. Plant Commun, 5: 100783. (corresponding author)
10. He Y, Han Y, Ma Y, Liu S, Fan T, Liang Y, Tang X, Zheng X, Wu Y, Zhang T*, Qi Y* and Zhang Y*. 2024a. Expanding plant genome editing scope and profiles with CRISPR-FrCas9 systems targeting palindromic TA sites. Plant Biotechnol J. (corresponding author)
11. Hui F, Tang X, Li B, Alariqi M, Xu Z, Meng Q, Hu Y, Wang G, Zhang Y*, Zhang X* and Jin S*. 2024. Robust CRISPR/Mb2Cas12a genome editing tools in cotton plants. iMeta, 3: e209. (corresponding author)
12. Liu S, He Y, Fan T, Zhu M, Qi C, Ma Y, Yang M, Yang L, Tang X, Zhou J, Zhong Z, An X*, Qi Y* and Zhang Y*. 2024. PAM-relaxed and temperature-tolerant CRISPR-Mb3Cas12a single transcript unit systems for efficient singular and multiplexed genome editing in rice, maize, and tomato. Plant Biotechnol J. (corresponding author)
13. Yang Q, Tang X, Wu Y, Zhu W, Zhang T* and Zhang Y*. 2024. CRISPR-based modulation of uORFs in DEP1 and GIF1 for enhanced rice yield traits. Rice (N Y), 17: 67. (corresponding author)
14. Zhang R, Tang X, He Y, Li Y, Wang W, Wang Y, Wang D, Zheng X, Qi Y* and Zhang Y*. 2024. IsDge10 is a hypercompact TnpB nuclease that confers efficient genome editing in rice. Plant Commun: 101068. (corresponding author)
15. Zheng X, Tang X, Wu Y, Zheng X, Zhou J, Han Q, Tang Y, Fu X, Deng J, Wang Y, Wang D, Zhang S, Zhang T*, Qi Y* and Zhang Y*. 2024. An efficient CRISPR-Cas12a-mediated MicroRNA knockout strategy in plants. Plant Biotechnol J. (corresponding author)
16. He Y, Han Y, Ma Y, Liu S, Fan T, Liang Y, Tang X, Zheng X, Wu Y, Zhang T*, Qi Y* and Zhang Y*. 2024. Expanding plant genome editing scope and profiles with CRISPR-FrCas9 systems targeting palindromic TA sites. Plant Biotechnol J. (corresponding author)
17. Tang X, Ren Q, Yan X, Zhang R, Liu L, Han Q, Zheng X, Qi Y*, Song H* and Zhang Y*. 2024. Boosting genome editing in plants with single transcript unit surrogate reporter systems. Plant Commun: 100921. (corresponding author)
18. Zhong Z, Fan T, He Y, Liu S, Zheng X, Xu Y, Ren J, Yuan H, Xu Z and Zhang Y*. 2024. An improved plant prime editor for efficient generation of multiple-nucleotide variations and structural variations in rice. Plant Commun: 100976. (corresponding author)
19. Han Y, Liu G, Wu Y, Bao Y, Zhang Y* and Zhang T*. 2023. CrisprStitch: Fast evaluation of the efficiency of CRISPR editing systems. Plant Commun: 100783. (corresponding author)
20. Zhong Z, Liu G, Tang Z, Xiang S, Yang L, Huang L, He Y, Fan T, Liu S, Zheng X, Zhang T, Qi Y*, Huang J* and Zhang Y*. 2023. Efficient plant genome engineering using a probiotic sourced CRISPR-Cas9 system. Nat Commun, 14: 6102. (corresponding author)
21. Tang X and Zhang Y*. 2023. Beyond knockouts: fine-tuning regulation of gene expression in plants with CRISPR-Cas-based promoter editing. New Phytol, 239: 868-874. (corresponding author)
22. Zhou J, Liu G, Zhao Y, Zhang R, Tang X, Li L, Jia X, Guo Y, Wu Y, Han Y, Bao Y, He Y, Han Q, Yang H, Zheng X, Qi Y*, Zhang T*, Zhang Y*. 2023. An efficient CRISPR–Cas12a promoter editing system for crop improvement. Nature Plants, 9: 588-604. (corresponding author)
23. Zheng X, Zhang S, Liang Y, Zhang R, Liu L, Qin P, Zhang Z, Wang Y, Zhou J, Tang X, Zhang Y*. 2023. Loss-function mutants of OsCKX gene family based on CRISPR-Cas systems revealed their diversified roles in rice. Plant Genome: e20283. (corresponding author)
24. Liu S, Sretenovic S, Fan T, Cheng Y, Li G, Qi A, Tang X, Xu Y, Guo W, Zhong Z, He Y, Liang Y, Han Q, Zheng X, Gu X, Qi Y*, Zhang Y*. 2022. Hypercompact CRISPR-Cas12j2 (CasΦ) enables genome editing, gene activation, and epigenome editing in plants. Plant Commun, 3: 100453. (corresponding author)
25. Wu Y, Ren Q, Zhong Z, Liu G, Han Y, Bao Y, Liu L, Xiang S, Liu S, Tang X, Zhou J, Zheng X, Sretenovic S, Zhang T*, Qi Y*, Zhang Y*. 2022. Genome-wide analyses of PAM-relaxed Cas9 genome editors reveal substantial off-target effects by ABE8e in rice. Plant Biotechnol J, 20: 1670-1682. (corresponding author)
26. Zhou J, Zhang R, Jia X, Tang X, Guo Y, Yang H, Zheng X, Qian Q*, Qi Y*, Zhang Y*. 2022. CRISPR-Cas9 mediated OsMIR168a knockout reveals its pleiotropy in rice. Plant Biotechnology Journal, 10.1111/pbi.13713. (corresponding author)
27. Wu Y, He Y, Sretenovic S, Liu S, Cheng Y, Han Y, Liu G, Bao Y, Fang Q, Zheng X, Zhou J, Qi Y*, Zhang Y*, Zhang T*. 2021. CRISPR-BETS: a base-editing design tool for generating stop codons. Plant Biotechnology Journal, 10.1111/pbi.13732. (corresponding author)
28. Ren Q, Simon S, Liu S, Tang X, Huang L, He Y, Liu L, Guo Y, Zhong Z, Liu G, Cheng Y, Zheng X, Pan C, Yin D, Zhang Y, Li W, Qi W, Li C, Qi Y*, Zhang Y*. 2021. PAM-less plant genome editing using a CRISPR-SpRY toolbox. Nature Plants, doi:10.1038/s41477-020-00827-4. (corresponding author)
29. Ren Q, Sretenovic S, Liu G, Zhong Z, Wang J, Huang L, Tang X, Guo Y, Liu L, Wu Y, Zhou J, Zhao Y, Yang H, He Y, Liu S, Yin D, Mayorga R, Zheng X, Zhang T*, Qi Y*, Zhang Y*. 2021. Improved plant cytosine base editors with high editing activity, purity, and specificity. Plant Biotechnology Journal, 10.1111/pbi.13635. (corresponding author)
30. Zhou J, Yuan M, Zhao Y, Quan Q, Yu D, Yang H, Tang X, Xin X, Cai G, Qian Q, Qi Y*, Zhang Y*. 2021. Efficient deletion of multiple circle RNA loci by CRISPR-Cas9 reveals Os06circ02797 as a putative sponge for OsMIR408 in rice. Plant Biotechnology Journal, 19: 1240-1252. (corresponding author)
31. Zhang Y, Ren Q, Tang X, Liu S, Malzahn AA, Zhou J, Wang J, Yin D, Pan C, Yuan M, Huang L, Yang H, Zhao Y, Fang Q, Zheng X, Tian L, Cheng Y, Le Y, McCoy B, Franklin L, Selengut JD, Mount SM, Que Q, Zhang Y*, Qi Y*. 2021. Expanding the scope of plant genome engineering with Cas12a orthologs and highly multiplexable editing systems. Nature Communications, 12: 1944. (corresponding author)
32. Tang X, Sretenovic S, Ren Q, Jia X, Li M, Fan T, Yin D, Xiang S, Guo Y, Liu L, Zheng X, Qi Y*, Zhang Y*. 2020. Plant prime editors enable precise gene editing in rice cells. Molecular Plant, doi:10.1016/j.molp.2020.03.010. (corresponding author)
33. Ming M, Ren Q, Pan C, He Y, Zhang Y, Liu S, Zhong Z, Wang J, Malzahn A, Wu J, Zheng X, Zhang Y*, Qi Y*. 2020. CRISPR-Cas12b enables efficient plant genome engineering. Nature Plants, 6: 202-208. doi:10.1038/s41477-020-0614-6. (corresponding author)
34. Zhou J, Xin X, He Y, Chen H, Li Q, Tang X, Zhong Z, Deng K, Zheng X, Akher SA, Cai G, Qi Y*, Zhang Y*. 2019. Multiplex QTL editing of grain-related genes improves yield in elite rice varieties. Plant Cell Reports, 38(4): 475-485. doi: 10.1007/s00299-018-2340-3. (corresponding author)
35. Zhong Z, Sretenovic S, Ren Q, Yang L, Bao Y, Qi C, Yuan M, He Y, Liu S, Liu X, Wang J, Huang L, Wang Y, Baby D, Wang D, Zhang T, Qi Y*, Zhang Y*. 2019. Improving plant genome editing with high-fidelity xCas9 and non-canonical PAM-targeting Cas9-NG. Molecular Plant, 12(7): 1027-1036. doi: 10.1016/j.molp.2019.03.011. (corresponding author)
36. Tang X, Ren Q, Yang L, Bao Y, Zhong Z, He Y, Liu S, Qi C, Liu B, Wang Y, Sretenovic S, Zhang Y, Zheng X, Zhang T*, Qi Y*, Zhang Y*. 2019. Single transcript unit CRISPR 2.0 systems for robust Cas9 and Cas12a mediated plant genome editing. Plant Biotechnology Journal, 17(7): 1431-1445. doi: 10.1111/pbi.13068. (corresponding author)
37. Tang X, Liu G, Zhou J, Ren Q, You Q, Tian L, Xin X, Zhong Z, Liu B, Zheng X, Zhang D, Malzahn A, Gong Z, Qi Y*, Zhang T*, Zhang Y*. 2018. A large-scale whole-genome sequencing analysis reveals highly specific genome editing by both Cas9 and Cpf1 (Cas12a) nucleases in rice. Genome Biology, 19(1): 84. doi: 10.1186/s13059-018-1458-5. (corresponding author)
38. Zhong Z, Zhang Y, You Q, Tang X, Ren Q, Liu S, Yang L, Wang Y, Liu X, Liu B, Zhang T, Zheng X, Le Y, Zhang Y*, Qi Y*. 2018. Plant genome editing using FnCpf1 and LbCpf1 nucleases at redefined and altered PAM sites. Molecular Plant, 11(7): 999-1002. doi: 10.1016/ j.molp.2018.03.008. (corresponding author)
39. Lowder LG, Zhou J, Zhang Y, Malzahn A, Zhong Z, Hsieh TF, Voytas DF, Zhang Y*, Qi Y*. 2018. Robust transcriptional activation in plants using multiplexed CRISPR-Act2.0 and mtale-act systems. Molecular Plant, 11(2): 245-256. doi: 10.1016/j.molp.2017.11.010. (corresponding author)
40. Tang X, Lowder LG, Zhang T, Malzahn A, Zheng X, Voytas DF, Zhong Z, Chen Y, Ren Q, Li Q, Kirkland ER, Zhang Y*, Qi Y*. 2017. A CRISPR-Cpf1 system for efficient genome editing and transcriptional repression in plants. Nature Plants, 3: 17018. doi:10.1038/nplants.2017.18. (corresponding author)
41. Tang X, Zheng X, Qi YP, Zhang D, Cheng Y, Tang A, Voytas DF*, Zhang Y*. 2016. A single transcript CRISPR-Cas9 system for efficient genome editing in plants. Molecular Plant, 9(7): 1088-1091. doi:10.1016/j.molp.2016.05.001. (corresponding author)
42. Lowder LG, Zhang D, Baltes NJ, Paul JW 3rd, Tang X, Zheng X, Voytas DF, Hsieh TF, Zhang Y*, Qi Y*. 2015. A CRISPR/Cas9 toolbox for multiplexed plant genome editing and transcriptional regulation. Plant Physiology, 169(2): 971-985. doi: 10.1104/pp.15.00636. (corresponding author)
43. Qi YP*, Zhang Y*, Zhang F, Baller JA, Cleland SC, Ryu Y, Starker CG, Voytas DF. 2013. Increasing frequencies of site-specific mutagenesis and gene targeting in Arabidopsis by manipulating DNA repair pathways. Genome Research, 23(3): 547-554. (equal contribution)
44. Shan QW, Wang YP, Chen KL, Liang Z, Li J, Zhang Y, Zhang K, Liu JX, Voytas DF, Zheng XL, Zhang Y*, Gao CX*. 2013. Rapid and efficient gene modification in rice and Brachypodium using TALENs. Molecular Plant, 6(4): 1365-1368. doi: 10.1093/mp/sss162 (Corresponding author)
45. Zhang Y, Zhang F, Li XH, Christian M, Bogdanove AJ, Qi YP, Starker CG, Bogdanove AJ, Voytas DF. 2013. Transcription activator-like effector nucleases enable efficient plant genome engineering. Plant Physiology, 161(1):20-27.
招生&招聘
1. PGE Lb真诚欢迎立志于从事植物基因组编辑及合成生物学的优秀硕博士研究生报考；
2. 实验室常年招收博士后，待遇从优；
3. 欢迎从事植物分子生物学、基因组工程、生物信息学等相关研究的青年俊才加入课题组。
联系方式
E-mail：zhangyong916@swu.edu.cn；zhangyong916@uestc.edu.cn