唐岳立

博士，讲师。

主要研究方向：

植物代谢调控和代谢工程，植物合成生物学

博士期间主要从事蔬菜维生素E合成途径暨代谢工程研究，博士后期间主要从事激素调控青蒿素代谢途径的机制研究。本人具有扎实的生物化学、分子生物学、植物生理学等专业理论基础，并熟练掌握基因克隆、遗传转化、蛋白分析、代谢产物提取分析等分子生物学和分析化学研究技术。

学习、工作经历

2020.11至今，西南大学生命科学学院，讲师。

2014.10-2020.09：上海交通大学，农业与生物学院，博士后。

2007.9–2014.9：上海交通大学，植物学专业，博士(硕博连读)。

2003.9–2007.6：四川大学，生物技术专业，本科

主持或参加科研项目情况(按时间倒序排序)：

1. 国家重点研发计划“合成生物学”专项（2018YFA0900600），重要活性代谢物在植物底盘中的高效定向合成，2019.07-2024.06，594万元，在研，参与；

2.国际合作项目(美国比尔及梅琳达·盖茨基金会项目)，Identification and functional characterization of putative enzymes involved in the artemisinin biosynthesis fromArtemisia annua,2018.09-2020.07，75万美元（514万元），在研，主要参与人；

3.中国博士后科学基金面上项目（2016M591664），植物激素乙烯和赤霉素调控青蒿素代谢途径的机制研究，2016.05-2017.09，5万元，已结题，主持；

4.国家863计划重点项目（2011AA100605），植物代谢产物生物反应器产品研发，2011.01-2016.12，861万元，已结题，主要参与人；

5.国家973计划重点项目（2007CB108805），农作物特殊营养品质的代谢工程，2007.01-2011.08，565万元，已结题，主要参与人。

主要科研成果：

期刊论文

1.Yueli Tang, Yue Wang, Chunxue Jiang, Zongyou Lv, Xueqing Fu, Qian shen, Tingxiang Yan, Guofeng Wang, Xiaofen Sun, Fangyuan Zhang*, Kexuan Tang*. A R3 MYB-like transcription factor, AaMYBL1, negatively regulates glandular trichome initiation and anthocyanin biosynthesis inArtemisia annua,Plant Physiology(under review)

2.Yueli Tang, Ling Li, Tingxiang Yan Xueqing Fu, Pu Shi, Qian Shen, Xiaofen Sun, Kexuan Tang^*(2018). AaEIN3 mediates the downregulation of artemisininbiosynthesis by ethylene signaling through promoting leaf senescenceinArtemisia annua,Frontiers in Plant Science9: 413. doi: 10.3389/fpls.2018.00413

3.Yueli Tang, Xueqing Fu, Qian Shen, Kexuan Tang^*(2016). Roles of MPBQ-MT inpromoting α/γ-tocopherol production and photosynthesis under high light inlettuce,PLoS ONE11(2): e0148490

4.Yueli Tang,Weiwei Ren, Lida Zhang, Kexuan Tang^*(2011). Molecular cloningand characterization of atocopherol cyclase gene from Lactuca sativa.Geneticsand Molecular Research10(2): 693-702.

5.Yueli Tang, Weiwei Ren, Lida Zhang, Kexuan Tang^*(2011). Molecular cloningand characterization of gene coding for γ-tocopherol methyl transferase fromlettuce.Genetics and Molecular Research10(4): 3204-3212.

6.Chen, M., Yan, T., Ji, L., Dong, Y., Sidoli, S., Yuan, Z., Cai, C., Chen, J.,Tang, Y., Shen, Q., Pan, Q., Fu, X., Ku, X., Liao, L., Garcia, B.A., Yan, W.* and Tang, K.* (2020). Comprehensive Map of theArtemisia annuaProteome and Quantification of Differential Protein Expression in Chemotypes Producing High versus Low Content of Artemisinin.Proteomicshttps://doi.org/10.1002/pmic.201900310

7. Ma, Y., Xu, D., Li, L., Zhang, F., Fu, X., Shen, Q., Lyu, X., Wu, Z., Pan, Q., Shi, P., Hao, X., Yan, T., Chen, M., Liu, P., He, Q., Xie, L., Zhang, Y.,Tang, Y., Zhao, J., Zhang, L., Sun, X. and Tang, K.* (2018). Jasmonate promotes artemisinin biosynthesis by activating the TCP14-ORA complex inArtemisia annua.Science Advances4, eaas9357.

8.Shen, Q., Zhang, L., Liao, Z., Wang, S., Yan, T., Shi, P., Liu, M., Fu, X., Pan, Q., Wang, Y., Lv, Z., Lu, X., Zhang, F., Jiang, W., Ma, Y., Chen, M., Hao, X., Li, L.,Tang, Y., Lv, G., Zhou, Y., Sun, X., Brodelius, P.E., Rose, J.K.C and Tang, K.* (2018). The genome ofArtemisia annuaprovides insight into the evolution of Asteraceae family and artemisinin biosynthesis.Molecular Plant11: 776-788.

9. Shi, P., Fu, X., Shen, Q., Liu, M., Pan, Q.,Tang, Y., Jiang, W., Lv, Z., Yan, T., Ma, Y., Chen, M., Hao, X., Liu, P., Li, L., Sun, X. and Tang, K.* (2018). The role ofAaMIXTA1in regulating the initiation of glandular trichomes and cuticle biosynthesis inArtemisia annua.New Phytologist217:261-276.

10. Yan, T., Li, L., Xie, L., Chen, M., Shen, Q., Pan, Q., Fu, X., Shi, P.,Tang, Y., Huang, H., Huang, Y., Huang, Y. and Tang, K.* (2018). A novel HD-ZIP IV/MIXTA complex promotes glandular trichome initiation and cuticle development inArtemisia annua.New Phytologist218: 567–578.

11.Fu, X., Shi, P., He, Q., Shen, Q.,Tang, Y., Pan, Q., Ma, Y., Yan, T., Chen, M., Hao, X., Liu, P, Li, L., Wang, Y., Sun, X. and Tang, K.* (2017).AaPDR3, a PDR transporter 3, is involved in sesquiterpene β-caryophyllene transport inArtemisia annua.Frontiers in Plant Science8:723 doi: 10.3389/fpls.2017.00723

12.Yan, T., Chen, M., Shen, Q., Li, L., Fu, X., Pan, Q.,Tang, Y., Shi, P., Lv, Z., Jiang, W., Ma, Y., Hao, X., Sun, X. and Tang, K.* (2017). HOMEODOMAIN PROTEIN 1 is required for jasmonate-mediated glandular trichome initiation inArtemisia annua.New Phytologist213(3): 1145-1155.

13.Chen, M., Yan, T., Shen, Q., Lu, X., Pan, Q., Huang, Y.,Tang, Y., Fu, X., Liu, M., Jiang, W., Lv, Z., Shi, P., Ma, Y., Hao, X., Zhang, L., Li, L. and Tang, K.* (2017). GLANDULAR TRICHOME-SPECIFIC WRKY 1 promotes artemisinin biosynthesis inArtemisia annua.New Phytologist214(1): 304-316.

14.Fu, X., Shi, P., Shen, Q., Jiang, W.,Tang, Y., Lv, Z., Yan, T., Li, L., Wang, G., Sun, X. and Tang, K.* (2016).T-shaped trichome-specific expression of monoterpene synthase ADH2 using promoter–β-GUS fusion in transgenicArtemisia annuaL.Biotechnology and Applied Biochemistry63(6): 834-840.

15. Jiang, W., Fu, X., Pan, Q.,Tang, Y., Shen, Q., Lv, Z., Yan, T., Shi, P., Li, L., Zhang, L., Wang, G., Sun, X. and Tang, K.* (2016). Overexpression ofAaWRKY1Leads to an Enhanced Content of Artemisinin inArtemisia annua.BioMed Research International2016: 1-9,

16. 郭新波,唐岳立,孙小芬,唐克轩^*(2011).高等植物维生素C和维生素E代谢调控.植物生理学报47(8): 731-744.

专利

1.唐岳立, 唐克轩, 任薇薇, 王玥月, 生菜γ-生育酚甲基转移酶蛋白编码序列, 2010.11.3-2014.4.9,中国, CN200910046353.4

2.唐岳立,唐克轩,任薇薇,王玥月,生菜生育酚环化酶蛋白编码序列, 2011.6.8-2015.5.13,中国, CN20 0910047783.8

3.唐岳立,唐克轩,任薇薇,生菜植醇激酶蛋白编码序列, 2012.7.4-2016.4.6,中国, CN200910046352.X

4.唐岳立,唐克轩,任薇薇,生菜MPBQ-MT蛋白编码序列, 2010.12.8-2015.1.7,中国, CN200810203448. 8

5.唐克轩,王玥月,唐岳立, cyp7lav1基因启动子, 2010.12.8-2018.12.25,中国, CN200910045041.1

6.唐克轩,付雪晴,石璞,唐岳立,沈乾,孙小芬,颜廷祥,吕宗友,一种调控基因在分泌型腺毛中表达的启动子及其应用, 2018.3.6,中国, CN201510409960.8

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